Instructions:

Genetic Marker Database:

An excellent source for listings of genetic markers, phenotypic traits affected, mapping data, and references is: Holloway, B.W., U. Rohmling and B. Tummler, 1994. Genomic mapping of Pseudomonas aeruginosa PAO. Microbiology 140: 2907-2929.

We have adapted Table 1, Markers located on the genetic and physical maps of P. aeruginosa PAO, from this paper to a database that you can search.  The genetic and physical map locations that the search tool will retrieve correspond to Figures 1 & 2 from the paper.  

There are two ways to search the genetic marker database:

1. Genetic Marker Search:

Similar to searching the strain database by genotype, the more specific you are the less matches you will see. For example, searching for "met" will yield more matches than searching for "met-28". You will get a listing of all markers known at the time of publication of the paper. If you get no matches on your first attempt, try using only the three letter marker designation or searching by phenotype (see below). Only enter one marker designation at a time in the search field. The database is searching for any string of characters containing your search entry, and the chances of you getting the marker designations, numbers, and spacing of more than one genotype exactly the same as the database entry are very slight.

2. Phenotype Keyword Search:

If you are looking for the markers associated with a particular phenotypic trait, this search may help you find them.  It searches for the characters you enter anywhere in the "Phenotypic Trait Affected" field of the genetic marker database. It is best to enter single words, because it is hard to mimic the ordering, spacing and punctuation of the actual database text.  If you get no results on your first attempt, try reducing the amount of information in the search box and resubmitting your search.

How to use results:

When you view the matches to each of your searches, you will be given the opportunity to search the strain and cosmid databases for that marker. The marker designations in the table of results are links to these search tools.  Simply click on the marker designation, and you will be taken to a page where you can choose to search either for strains or cosmids.  For more information on searching the strain and cosmid databases, please return to the main instructions page and follow the links to the appropriate instructions, or choose a link below.

If you have difficulty searching the database or submitting your request, please feel free to e-mail your request to the curator at Pseudomonas@mail.ecu.edu. You can also mail or fax requests or comments to:

 

 

Robin Alligood,  Curator
Pseudomonas Genetic Stock Center
East Carolina University School of Medicine
Biotechnology Program
Greenville, NC 27858
fax#: (252) 744-3535

 

 

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